You are here

Article Text

Article menu
Download PDFPDF
A non-isotopic method for the detection of telomerase activity in tumour tissues: TRAP-silver staining assay.
  1. J M Wen,
  2. L B Sun,
  3. M Zhang,
  4. M H Zheng
  1. Department of Pathology, Sun Yat-Sen University of Medical Sciences, Guangzhou, People's Republic of China.

    Abstract

    Telomerase activity has been observed in a high proportion of specimens from a wide variety of human malignant tumours, but not in non-neoplastic tissues. Measurement of telomerase activity is a possible diagnostic maker for malignant tumours. A non-isotopic telomeric repeat amplification protocol (TRAP) silver staining method for the detection of telomerase activity in human bone tumour tissues is described. The TRAP-silver staining method was quick, safe, and effective, and can be used as a routine diagnostic method for the detection of telomerase activity in bone tumours.

    https://doi.org/10.1136/mp.51.2.110

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.