Article Text
The aetiology of idiopathic Parkinson's disease
Abstract
Agents potentially involved in the aetiology of idiopathic Parkinson's disease are discussed. These include factors regulating dopaminergic neurogenesis (Nurr 1, Ptx-3, and Lmx1b) and related proteins, together with genes involved in familial Parkinson's disease (α synuclein, parkin, and ubiquitin carboxy terminal hydroxylase L1), and endogenous and environmental agents.
- Parkinson's disease
- environmental agents
- transcription factors
- α synuclein
- parkin
- ubiquitin carboxy terminal hydroxylase L1