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p21: prognostic marker in pleural mesothelioma

https://doi.org/10.1136/mp.55.4.234

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    Mesothelioma stained with monoclonal antibody to p21. (A) Mixed mesothelioma with ≤10% of positive cells; (B) sarcomatoid mesothelioma with >10% positive cells. Original magnification ×400.

    Expression of p21—an inhibitor of the cell cycle—may hold an important clue to events leading to malignant mesothelioma. Normally p21 expression is upregulated by the binding of …

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