Summary
Using a fragment of the cDNA for human coagulation factor VIII as a hybridization probe, we have detected a new polymorphic Hind III site in intron 19 of the factor VIII gene. The frequency of the minor allele is 0.30. This polymorphism shows strong linkage disequilibrium with a previously described BclI polymorphism in intron 18.
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Ahrens, P., Kruse, T.A., Schwartz, M. et al. A new Hind III restriction fragment length polymorphism in the hemophilia A locus. Hum Genet 76, 127–128 (1987). https://doi.org/10.1007/BF00284907
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DOI: https://doi.org/10.1007/BF00284907