Differences in the staining scores of proteinases and inhibitors in each cell type of 44 breast tumours as assessed by immunohistochemistry
| Tumour cells | Fibroblasts | Inflammatory cells | |
|---|---|---|---|
| Values are mean (range). *p<0.05; Wilcoxon signed rank test for related samples. | |||
| MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinases; tPA, tissue-type plasminogen activator; uPA, urokinase-type plasminogen activator. | |||
| MMP-1 | 1.8 (1–4)* | 1.3 (1–3) | 1.1 (1–3) |
| MMP-2 | 2.3 (1–4)* | 1.5 (1–2) | 1.3 (1–2) |
| MMP-3 | 1.6 (1–4)* | 1.2 (1–3) | 1.1 (1–3) |
| MMP-9 | 1.6 (1–3) | 1.6 (1–4) | 1.3 (1–4) |
| uPA | 2 (1–4) | 1.7 (1–4) | 1.2 (1–2) |
| tPA | 1.7 (1–4)* | 1.5 (1–3) | 1.2 (1–3) |
| TIMP-1 | 2.9 (1–4)* | 1.9 (1–4) | 1.5 (1–4) |
| TIMP-2 | 3.2 (1–4)* | 2.1 (1–4) | 2.1 (1–4) |