Distribution of p53 mutation types in rectal and colorectal carcinomas
| Rectal | Colorectal | |||
|---|---|---|---|---|
| p53 mutation type | n | % | n | % |
| Non-confirmed codon 110 and 232 mutations (possible tumour mosaicism, see text) are excluded. | ||||
| Rectal results are from this study; colorectal results are from Hainaut et al.4 | ||||
| G:C → A:T at CpG | 20 | 49 | 277 | 49 |
| G:C → A:T at non-CpG | 2 | 5 | 95 | 17 |
| G:C → C:G | 1 | 2 | 16 | 3 |
| G:C → T:A | 4 | 10 | 54 | 9 |
| A:T → C:G | 0 | 0 | 10 | 2 |
| A:T → G:C | 3 | 7 | 47 | 8 |
| A:T → T:A | 3 | 7 | 24 | 4 |
| Deletions, insertions, complex | 8 | 20 | 45 | 8 |
| Total | 41 | 568 | ||