Clonal TCRγ gene rearrangements detected in samples from patients with T cell disease using both LIS-SSCP PAGE and DNA sequencer analysis of products labelled using fluorescent nucleotides
| Patient | Diagnosis | Clonal TCRγ gene rearrangements detected using LIS-SSCP PAGE and a DNA sequencer |
|---|---|---|
| LIS-SSCP PAGE, low ionic strength single strand conformation polymorphism polyacrylamide gel electrophoresis; TCR, T cell receptor. | ||
| 1 | Cutaneous T cell lymphoma | GV1Jγ and GV2Jγ |
| 2 | Cutaneous T cell lymphoma | GV1JγP and GV1JγP1/2 |
| 3 | T cell non-Hodgkin's lymphoma | GV3Jγ and GV4Jγ |
| 4 | T cell non-Hodgkin's lymphoma | GV1Jγ and GV1JγP |
| 5 | T cell non-Hodgkin's lymphoma | GV1JγP, GV2Jγ, GV2JγP1/2, GV3 JγP1/2, and GV4Jγ |
| 6 | T cell non-Hodgkin's lymphoma | GV1Jγ |
| 7 | T cell non-Hodgkin's lymphoma | GV1Jγ and GV2Jγ |
| 8 | Sezary syndrome | GV1JγP,GV2Jγ,GV2JγP1/2,GV3JγP1/2, GV4Jγ, and GV4JγP1/2 |
| 9 | T cell chronic lymphocytic leukaemia | GV1Jγ |
| 10 | T cell prolymphocytic leukaemia | GV2Jγ and GV3Jγ |
| 11 | T cell γδ hepatosplenic lymphoma | GV1Jγ |