Demographics and clinical features of patients with X linked dystonia parkinsonism (XDP)
| Variable | Data |
|---|---|
| These data are derived from the XDP Philippine Registry, 2000. | |
| Ages and durations are in years. | |
| No. of XDP cases registered 1975–2000 | 373 |
| No. of survivors November 2000 | 268 |
| Philippine population as of 2000 | 74.7 M |
| Prevalence of surviving cases/100 000 | 0.36 |
| Prevalence of cases in Capiz/100 000 | 21.94 |
| Prevalence of cases in Aklan/100 000 | 7.72 |
| Prevalence of cases in Iloilo/100 000 | 1.43 |
| Prevalence of cases in Antique/100 000 | 0.86 |
| Prevalence of cases in Guimaras/100 000 | 0.73 |
| No. of families | 187 |
| No. of cases with positive family history | 343 |
| No. of deaths | 105 |
| No. of cases that underwent necropsy | 6 |
| Sex, male/female (%) | 370 (99)/3 (1) |
| Mean age at onset (range) | 39.5 (12–64) |
| Mean age at initial examination (range) | 40.8 (20–70) |
| Mean duration of illness from onset to present mean (range) | 13.04 (1–41) |
| Mean duration of illness from onset to generalisation of dystonia (range) | 3.8 (1–23) |
| Mean duration of illness from onset to parkinsonism (range) | 13.39 (7–25) |
| Mean age of survivors (range) | 52.73 (28–86) |
| Mean age at death (range) | 52.06 (31–81) |
| No. initially presenting with parkinsonism (%) | 24 (6) |
| No. initially presenting with dystonia (%) | 349 (94) |
| Lower extremities | 122 (33) |
| Craniofacial | 102 (27) |
| Cervical and shoulder | 92 (25) |
| Upper extremities | 52 (14) |
| Trunk | 5 (1) |
| No. of cases, spread (%) | 363 (97) |
| No. of cases, generalised (%) | 313 (84) |
| No. of cases, parkinsonian (%) | 53 (14) |
| Degree of disability of survivors | |
| No. still working (%) | 13 (5) |
| No. ambulant, not working (%) | 192 (72) |
| No. non-ambulant; able to care for self (%) | 3 (1) |
| No. wheelchair and bed bound (%) | 60 (22) |