Characteristics of human acid phosphatases
| Human acid phosphatase (AP) | Tissue/cells cells of origin | M (kDa) | Gel band | Chromosome | Amino acid sequence | Amino acid homology | Tartrate resistance | Fluoride resistance4 |
|---|---|---|---|---|---|---|---|---|
| Gel band refers to the relative position of acid phosphatase after its migration towards the cathode in acidic polyacrylamide gel electrophoresis.1013 | ||||||||
| M, molecular mass. | ||||||||
| Lysosomal (LAP) | Most cells1 | 1001 | 32 | 111 | 4233 | 50% PAP3 | – | + |
| Prostatic (PAP) | Prostate gland, brain, spleen, liver, platelets | 1003 | 2b5 | 33 | 3453 | 50% LAP3 | – | + |
| Erythrocytic (EAP) | Erythrocytes, many cell types | 186 | 12 | 27 | 1578 | None known | + | + |
| Macrophage (MAP) | Macrophages of liver, spleen, lung | 379 | 510 | 199 | 3259 | High with OcAP12 | + | + |
| Osteoclastic (OcAP) | Osteoclasts of bone | 3711 | 510 | 199 | 3259 | High with MAP12 | + | – |