Molecular biological findings in relation to the leukaemia subtype
| Immunohistochemical diagnosis | Number of cases | Monoclonal rearrangement | % |
|---|---|---|---|
| AL, acute leukaemia; ALL, acute lymphoblastic leukaemia; AML, acute myelogenous leukaemia; B-ALL, B cell ALL; IgH, immunoglobulin heavy chain; T-ALL, T cell ALL; TCR-γ, T cell receptor γ; u-ALL, unclassified ALL. | |||
| B-ALL | n = 1 | 1 (IgH) | 100 |
| T-ALL | n = 7 | 5 (4 TCR-γ, 1 IgH) | 71 |
| c-ALL | n = 23 | 21 (19 IgH, 1 IgH + TCR-γ, 1 TCR-γ) | 91 |
| u-ALL | n = 4 | 4 (3 IgH, 1 IgH + TCR-γ) | 100 |
| ALL | n = 35 | 31 (26 IgH, 7 TCR-γ) | 89 |
| AL, biphenotypic | n = 3 | 2 (IgH) | 67 |
| AML | n = 10 | 2 (IgH) | 20 |