PCR detection of monoclonal, rearranged immunoglobulin genes in DNA extracted from randomly selected formalin fixed, paraffin wax embedded tissue samples
| Sample | Diagnosis | Igκ PCR | Igλ PCR | IgH PCR |
|---|---|---|---|---|
| DLBCL, diffuse large B cell lymphoma; FL, follicular lymphoma; M, monoclonal; MZL, marginal zone lymphoma; NLPHD, nodular lymphocyte predominant Hodgkin's lymphoma; P, polyclonal; SMZL, splenic marginal zone lymphoma. | ||||
| 1 | MZL | P | M | M |
| 2 | MZL | M | P | M |
| 3 | MZL | P | M | M |
| 4 | MZL | P | P | M |
| 5 | FL | P | P | M |
| 6 | FL | P | P | P |
| 7 | FL | M | P | P |
| 8 | SMZL | M | P | M |
| 9 | DLBCL | M | P | M |
| 10 | DLBCL | M | M | M |
| 11 | NLPHD | P | P | P |
| 12 | Reactive | P | P | P |
| Total | 5/12 | 3/12 | 8/12 | |
| Igκ/Igλ PCR | 7/12 | |||
| Igκ/Igλ/IgH PCR | 9/12 | |||