Table 4

Postoperative mutant serum KRAS2, tumour KRAS2 status, and recurrence in group B

Serum + (n (%))Recurrence rate (n (%))OR (95% CI)p Value
(+) and (−) refer to KRAS2 mutation status.
 †‡There was no significant difference in recurrence rates between tumour (+) and tumour (−) patients.
¶* In tumour (+) patients, disease recurrence was highly significantly increased in serum (+) compared with serum (−) patients.
All group B patients (n=94)16 (17)20 (21)
    Tumour + (n=60)16 (27)11 (18)‡0.35‡
    Tumour − (n=34) 0 (0) 9 (26) ‡
    Tumour +/serum + (n=16)10 (63)¶71.6 (7.7–663.9)¶0.0000¶
    Tumour +/serum – (n=44) 1 (2)¶
Group B subgroup only (n=85)15 (18)17 (20)
    Tumour + (n=54)15 (28)10 (19)†0.65†
    Tumour − (n=31) 0 (0) 7 (23) †
    Tumour +/serum + (n=15) 9 (60)*57 (6.1–534.5)*0.0000*
    Tumour +/serum − (n=39) 1 (3)*