Relation of increased cyclin D1 expression to clinicopathological features of 30 carcinomas of the ampulla of Vater
| Cyclin D1 expression | |||
|---|---|---|---|
| Increased | Normal or negative | p Value | |
| Values are mean (SD). | |||
| Histological grade: pap, papillary adenocarcinoma; well, well differentiated; mod, moderately differentiated; poor, poorly differentiated. | |||
| *Mann-Whitney U test; †two tailed Fischer’s exact test. | |||
| LI, labelling index. | |||
| Number | 17 | 13 | |
| Age (years) | 66.2 (8.2) | 62.9 (7.2) | 0.2575* |
| Sex (female/male) | 6/11 | 3/10 | 0.6908† |
| Histological grade (pap+well/mod+poor) | 6/11 | 9/4 | 0.0824† |
| Size | 25.5 (13.3) | 22.5 (5.4) | 0.9831* |
| Lymph node metastasis | 11 (64.7%) | 5 (38.5%) | 0.2685† |
| Clinical stage (stage I+II/III+IV) | 9/8 | 7/6 | 1† |
| MIB-1 LI | 50.1 (12.8) | 33.8 (20.6) | 0.018* |