Clinicopathological characteristics and their association with overall survival in 25 patients with metastatic gastric cancer
| Overall survival | ||||||
|---|---|---|---|---|---|---|
| Variable | Coding plan | N | Events | Censored | Survival (months) | Log rank |
| Regression score according to the Japanese Research Society for Gastric Cancer classification of gastric carcinoma30: 0, grade 0; 1a, grade 1a; 1b, grade 1b; 2, grade 2; 3, grade 3. p53 immunohistochemistry: 0, negative; 1, positive (nuclear expression in >10% of tumour cells). | ||||||
| Surgery | 0 No surgery | 9 | 8 | 1 | 7.5 | 0.0007 |
| 1 Surgery | 16 | 13 | 3 | 16.0 | ||
| Histological regression | 0 No regression | 14 | 13 | 1 | 8.2 | 0.0018 |
| 1 Regression | 11 | 8 | 3 | 18.8 | ||
| p53 mutation | 0 No p53 mutation | 17 | 15 | 2 | 10.2 | 0.0439 |
| 1 p53 mutation | 8 | 6 | 2 | 18.5 | ||
| p53 immunohistochemistry | 0 Negative | 11 | 10 | 1 | 7.2 | 0.0003 |
| 1 Positive | 14 | 11 | 3 | 17.3 | ||