Phylogeny and ontogeny of the phosphoglycerate mutases—I. Electrophoretic phenotypes of the glycerate-2,3-P2 dependent phosphoglycerate mutase in vertebrates

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Abstract

  • 1.

    1. The electrophoretic phenotype of phosphoglycerate mutase in tissues from different classes of vertebrates at several stages of development have been analyzed on cellulose acetate.

  • 2.

    2. Mammals, reptiles, amphibians and fish show a common three-banded isozyme pattern.

  • 3.

    3. The three isozymes vary in their relative distribution from tissue to tissue and during growth.

  • 4.

    4. In birds electrophoretically distinguishable phosphoglycerate mutase isozymes have not been detected.

  • 5.

    5. The results support a genetic basis for the phosphoglycerate mutase isozymes and suggest that gene duplication may have occurred early in vertebrate evolution.

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