Vascular endothelial growth factor expression in head and neck squamous cell carcinoma**
References (11)
- et al.
Vascular endothelial growth factor
J Bio Chem.
(1992) - et al.
Vascular endothelial growth factor (VEGF) mRNA expression in human tumor models of different histologies
Ann Oncol.
(1995) - et al.
Induction of vascular endothlial growth factor expression in synovial fobroblasts by pros-taglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis
FEBS Lett.
(1995) - et al.
Association of vascular endothelial growth factor expression with tumor angiogen-esis and with early relapse in primary breast cancer
Breast Can Res Treat.
(1994) - et al.
Expression of endothelial cell-specific receptor tyrosine kinases and growth factors in human brain tumors
Am J Path.
(1995)
Cited by (109)
Clinical immunotherapeutic approaches for the treatment of head and neck cancer
2019, International Journal of Oral and Maxillofacial SurgeryCitation Excerpt :They are the key regulators in tumour angiogenesis and therefore are associated with increased tumour invasion and metastasis. A correlation between high levels of VEGF and a poor prognosis has been shown in patients with various types of tumours39, including head and neck cancer (HNC)40. Therefore, inhibition of the VEGFR pathway has been suggested as a potential therapy in these patients.
Is there a pAkt between VEGF and oral cancer cell migration?
2014, Cellular SignallingEstablished and novel NF-κB inhibitors lead to downregulation of TLR3 and the proliferation and cytokine secretion in HNSCC
2011, Oral OncologyCitation Excerpt :The malignant transformation process of HNSCC is strongly associated with an altered response to cytokine stimulation and various cytokines are supposed to play an important role in the tumorigenesis and maintenance of head and neck cancer.1–9
Is VEGF a predictive biomarker to anti-angiogenic therapy?
2011, Critical Reviews in Oncology/HematologyCitation Excerpt :Numerous retrospective studies have been conducted in the attempt to evaluate the relationship between VEGF levels with disease stage and prognosis in various human malignancies. Increased VEGF expression, either in the circulation or in tumor tissue, was found to correlate with worse prognosis (decreased disease-free, relapse-free and/or survival) in several cancers including bladder [31], breast [23,32], cervical [24], colorectal [25,33], head and neck [34], lung [35], ovarian [36] and renal cell cancers [37], although a correlation was not seen in other studies. These different findings about the correlation of VEGF with prognosis make it difficult to draw definitive conclusions as to the prognostic value of VEGF measurement whether in tumor or in serum.
How to Treat Today? Oral and Facial Cancer-Associated Venous Thromboembolism
2023, Pharmaceuticals
- **
Presented at the 43rd Annual Meeting of the Society of Head and Neck Surgeons, Cancún, Mexico, April 10–12, 1997.