Structure
Volume 3, Issue 1, January 1995, Pages 1-6
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The first structure of a receptor tyrosine kinase domain:a further step in understanding the molecular basis of insulin action

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Abstract

Both the observed cis-inhibition and the proposed trans-activation of the insulin receptor tyrosine kinase help explain insulin signalling through its receptor.

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Neil Q McDonald, Judith Murray-Rust and Tom L Blundell, ICRF Unit for Structural Molecular Biology, Department of Crystallography, Birkbeck College, London WC1E 7HX, UK.