Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
Warthin tumor: A new hypothesis concerning its development
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Cited by (44)
Salivary Glands
2020, Gnepp's Diagnostic Surgical Pathology of the Head and Neck, Third EditionWarthin's tumour in oral and maxillofacial regions: an 18-year retrospective study of 1084 cases in an eastern-Chinese population
2018, International Journal of Oral and Maxillofacial SurgeryDiagnostic pitfalls of infarcted Warthin tumor in frozen section evaluation
2016, Annals of Diagnostic PathologyCitation Excerpt :In the early literature, WT was reported to have a distinct male predilection, with a male-to-female ratio of 10:1. But more contemporary studies have shown that WT had a similar incidence in female and male, with a 1:1 ratio [7,9]. This change is likely largely due to the increased prevalence of smoking in women in the past few decades.
An unexpected Warthin's tumor
2015, Annales de PathologieImmunoglobulin class switching to IgG4 in Warthin tumor and analysis of serum IgG4 levels and IgG4-positive plasma cells in the tumor
2014, Human PathologyCitation Excerpt :Although the epithelial component is generally believed to represent the neoplastic proliferation of salivary ducts, Honda et al [2] showed, using HUMARA (human androgen receptor gene) analysis, that the epithelial component of Warthin tumor was a polyclonal population, which indicates that Warthin tumor is a nonneoplastic lesion. Previous studies have shown that immune and inflammatory reactions [3] and lymphocytic infiltration [4] may occur in Warthin tumor, although whether and how B-cell immunity is related to the formation of the lymphoid component remains to be fully elucidated. Recently, we and others reported cases that revealed the infiltration of immunoglobulin (Ig)G4-positive plasma cells in Warthin tumor, which implied the possible relationship with IgG4-related disease (IgG4-RD) [5,6].
Salivary and lacrimal glands
2009, Diagnostic Surgical Pathology of the Head and Neck: Expert Consult - Online and Print