Abstract
The BC-1 strain DNA of Marek's disease virus type 1 (MDV1) at high-passage in culture was found to contain tandem direct repeats of the complete long terminal repeat (LTR) sequence of avian leukosis virus RAV0 strain as the repeat unit within the short inverted repeats of the MDV1 DNA. Since the attenuated BC-1 strain grows well in cultured cells, the insertion site for retroviral DNA sequence within the short inverted repeat of MDV1 DNA is not essential for viral growth in culture.
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Bacon L.D., Witter, R.L., and Fadly A.M., J Virol 63, 504–512, 1989.
Frankel J.W., and Groupe V., Nature New Biol 234, 125–126, 1971.
Peters W.P., Kufe D., Schlom J., Frankel J.W., Prickett C.O., Groupe V., and Spiegelman S., Proc Natl Acad Sci USA 70, 3175–3178, 1973.
Frazier J.A., J Natl Cancer Inst 52, 829–837, 1974.
Frankel J.W., Farrow W.F., Prickett C.0., Smith M.E., Campbell W.F., and Groupe V., J Natl Cancer Inst 52, 1491– 1497, 1974.
Jakovleva L.S., and Mazurenko N.P., Neoplasma 26, 393–396, 1979.
Aly M.M., Fadley A.M., and Witter R.L., Avian Pathology 25, 81–94, 1996.
Isfort R., Jones D., Kost R., Witter R., and Kung H.-J., Proc Natl Acad Sci USA 89, 991–995, 1992.
Kost R., Jones D., Isforet R., Witter R.L., and Kung H.-J., Virology 192, 161–169, 1993.
Jones D., Isfort R., Witter R., Kost R., and Kung H.-J., Proc Natl Acad Sci USA 90, 3855–3859, 1993.
Isfort R., Qian Z., Jones D., Silva R.F., Witter R., and Kung H.-J., Virology 203, 125–133, 1994.
Jones D., Brunovskis P., Witter R., and Kung H.-J., J Virology 70, 2460–2467, 1996.
Hirai K. in Kato S., Horiuchi T., Mikami T., and Hirai K. (eds.) Advances in Marek's Disease Research. Japanese Association of Marek's Disease, Osaka, 1988, pp. 21–42.
Hirai K., Ikuta, K., and Kato S., J Gen Virol 45, 119–131, 1979.
Zhu G.-S., Ojima T., Hironaka T., Ihara T., Mizukoshi N., Kato A., Ueda S., and Hirai K., Avian Dis 36, 637–645, 1992.
Sakaguchi M., Urakawa T., Hirayama Y., Miki N., Yamamoto M., Zhu G.-S., and Hirai K., Virology 195, 140–148, 1993.
Sakaguchi M., Hirayama Y., Maeda H., Matsuo K., Yamamoto M., and Hirai K., Vaccine 12, 953–957, 1994.
Maniatis T., Fritch E.F., and Sambrook J., Molecular Cloning. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1989.
Hirai K., Kanamori A., Niikura M., Ikuta K., and Kato S. in Kato S., Horiuchi T., Mikami T., and Hirai K. (eds.) Advances in Marek's Disease Research. Japanese Association of Marek's Disease, Osaka, 1988, pp. 140–147.
Sakaguchi K., Urakawa T., Hirayama Y., Miki N., Yamamoto M., and Hirai K., Virus Genes 6, 365–378, 1992.
Tsichlis P.N., Donehower L., Hager G., Zeller N., Malavalca R., Astrin S., and Skalka A.M., Mol Cell Biol 2, 1331–1338, 1982.
Sonoda K., Sakaguchi M., Matsuo K., Zhu G.-S., and Hirai K., Vaccine 14, 277–284, 1996.
Payne L.N. in Roizman B. (ed.) The herpesviruses, Vol. 1. Plenum, New York, 1982, pp. 347–431.
Anderson A.S., Francesconi A., and Morgan R.W., Virology, 189, 657–667, 1992.
Roizman B. in Roizman B., Whitley R.J., and Ropez C. (eds.) The human herpesvirus, Raven Press, New York, 1993, pp. 11–68.
Li D.-S., Pastorek J., Zelnik V., Smith G.D., and Ross L.J.N., J Gen Virol 75, 1713–1722, 1994.
Cantello J.L., Anderson A.S., and Morgan R.W., J Virol 68, 6280–6290, 1991.
McKie E.A., Ubukata E., Hasegawa S., Zhang S., Nonoyama M., and Tanaka A., J Virol 69, 1310–1314.
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Matsuo, K., Sonoda, K., Sakaguchi, M. et al. Insertion of Tandem Direct Repeats Consisting of Avian Leukosis Virus LTR Sequences into the Inverted Repeat Region of Marek's Disease Virus Type 1 DNA. Virus Genes 14, 157–162 (1997). https://doi.org/10.1023/A:1007925519587
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DOI: https://doi.org/10.1023/A:1007925519587