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Developmental biology

A twist on embryonic signalling

Gradients of signalling proteins control the formation of different tissues during animal development. A controversial model for how one such gradient is produced now receives more experimental support.

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Figure 1: During an early stage in the development of the fruitfly Drosophila melanogaster, different ectodermal tissues are induced by high, intermediate and low levels of activity of a bone morphogenetic protein, Decapentaplegic (Dpp)4.

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Correspondence to Richard M. Harland.

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Harland, R. A twist on embryonic signalling. Nature 410, 423–424 (2001). https://doi.org/10.1038/35068657

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