Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Product Review
  • Published:

Multiplexed biochemical assays with biological chips

Nature volume 364, pages 555–556 (1993)Cite this article

High density peptide and oligonucleotide chips are fabricated using semiconductor-based technologies. These chips have a variety of biological applications.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Fodor, S. P. A., Read, J. L., Pirrung, M. C., Stryer, L., Lu, A. T. & Solas, D. Science 251, 767–773 (1991).

    Article  ADS  CAS  Google Scholar 

  2. Pease, A. C., Solas, D., Sullivan, E. J., Cronin, M. T., Holmes, C. P. & Fodor, S. P. A. (Submitted).

  3. Holmes, C. P., Adams, C. L., Fodor, S. P. A. & Yu-Yang, P. in Perspectives in Medicinal Chemistry (eds Testa, B., Kyburz, E., Fuhrer, W. & Giger, R.) 489–500 (Verlag Helvetica Chimica Acta, Basel, 1993).

    Google Scholar 

  4. Lysov, Yu. P., Florentiev, V. L., Khorlyn, A. A., Khrapko, K. R., Shick, V. V. & Mirzabekov, A. D. Dokl. Akad. Nauk SSSR 303, 1508–1511 (1988).

    CAS  PubMed  Google Scholar 

  5. Bains, W. & Smith, G. C. J. theor. Biol. 135, 303–307 (1988).

    Article  CAS  Google Scholar 

  6. Drmanac, R., Labat, I. I., Brukner, I. I. & Crkvenjakov, R. Genomics 4, 114–128 (1989).

    Article  CAS  Google Scholar 

  7. Drmanac, R. et al. Science 260, 1649–1652 (1993).

    Article  ADS  CAS  Google Scholar 

  8. Southern, E. M., Maskos, U. & Elder, J. K. Genomics 13, 1008–1017 (1992).

    Article  CAS  Google Scholar 

  9. Huang, X. Y., Lipshutz, R. & Fodor, S. P. A. (in preparation).

Download references

Author information

Authors and Affiliations

  1. Affymetrix, 3380 Central Expressway, Santa Clara, Calfornia, 95051, USA

    Stephen P. A. Fodor, Richard P. Rava & Xiaohua C. Huang

  2. Affymax, 4001 Miranda Avenue, Pa/o Alto, California, 94304, USA

    Stephen P. A. Fodor, Richard P. Rava, Ann C. Pease, Christopher P. Holmes & Cynthia L. Adams

Authors
  1. Stephen P. A. Fodor
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Richard P. Rava
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Xiaohua C. Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ann C. Pease
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Christopher P. Holmes
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Cynthia L. Adams
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fodor, S., Rava, R., Huang, X. et al. Multiplexed biochemical assays with biological chips. Nature 364, 555–556 (1993). https://doi.org/10.1038/364555a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/364555a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing