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Host factors and the pathogenesis of HIV-induced disease

Abstract

The level of human immunodeficiency virus (HIV) replication in patients reflects a balance between stimulatory and inhibitory host factors (particularly endogenous cytokines). New information concerning the cellular co-receptors for HIV and the cellular tropism of different strains of virus will advance our understanding of HIV-induced pathogenesis and suggests new therapeutic and preventive strategies.

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Linda-Gail Bekker, Chris Beyrer, … Jeffrey V. Lazarus

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Fauci, A. Host factors and the pathogenesis of HIV-induced disease. Nature 384, 529–534 (1996). https://doi.org/10.1038/384529a0

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