Increased expression of novel full-length endogenous mink cell focus-forming-related transcripts in autoimmune mouse strains

A M Krieg; A D Steinberg; A S Khan

doi:10.1016/0042-6822(88)90422-9

Increased expression of novel full-length endogenous mink cell focus-forming-related transcripts in autoimmune mouse strains

Virology. 1988 Jan;162(1):274-6. doi: 10.1016/0042-6822(88)90422-9.

Authors

A M Krieg¹, A D Steinberg, A S Khan

Affiliation

¹ Cellular Immunology Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, Maryland 20892.

PMID: 2827386
DOI: 10.1016/0042-6822(88)90422-9

Abstract

We have identified a novel 8.4-kb retroviral transcript which represents an endogenous mink cell focus-forming env-related provirus containing a 190-bp cellular DNA insert in the LTR region. This RNA species was highly expressed in tissues of autoimmune mouse strains, but not in those of nonautoimmune strains.

MeSH terms

Animals
Autoimmune Diseases / microbiology*
Gene Expression Regulation
Leukemia Virus, Murine / genetics*
Mice
Mice, Inbred Strains
RNA, Messenger / genetics
Transcription, Genetic
Viral Envelope Proteins / genetics

Substances

RNA, Messenger
Viral Envelope Proteins