Abstract
Serum samples from 43 cases of Guillain-Barré Syndrome (GBS), 32 non-GBS neurology patients, and 35 healthy persons from a medical institute in Kerala, India, were tested for antibody levels against a Campylobacter jejuni strain Penner serotype 0:19 by agglutination and ELISA. Twenty-six percent of samples from GBS cases showed high antibody levels in all assays. Of 8 stool samples of new GBS cases examined by culture, 38% were positive for C. jejuni/C. col1. The results suggest that at least a quarter of GBS cases studied were associated with Campylobacter infection.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Antibodies, Bacterial / blood
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Autoantibodies / blood
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Campylobacter Infections / microbiology*
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Campylobacter jejuni / immunology
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Campylobacter jejuni / isolation & purification*
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Child
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Escherichia coli / isolation & purification*
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Escherichia coli Infections / microbiology
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Feces / microbiology
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Female
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G(M1) Ganglioside / immunology
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Humans
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Male
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Middle Aged
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Polyradiculoneuropathy / immunology
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Polyradiculoneuropathy / microbiology*
Substances
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Antibodies, Bacterial
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Autoantibodies
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G(M1) Ganglioside