Cyclin D1 in breast cancer
DM Barnes, CE Gillett - Breast cancer research and treatment, 1998 - Springer
Cyclin D1 protein plays an important part in regulating the progress of the cell during the G1
phase of the cell cycle. The cyclin D1 gene, CCND1, is amplified in approximately 20% of …
phase of the cell cycle. The cyclin D1 gene, CCND1, is amplified in approximately 20% of …
Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some …
PA Hall, DA Levison, AL Woods, CCW Yu… - The Journal of …, 1990 - Wiley Online Library
Proliferating cell nuclear antigen (PCNA) is a 36 kD nuclear protein associated with the cell
cycle. A monoclonal antibody, PC10, that recognizes a fixation and processing resistant …
cycle. A monoclonal antibody, PC10, that recognizes a fixation and processing resistant …
BRCA1 dysfunction in sporadic basal-like breast cancer
NC Turner, JS Reis-Filho, AM Russell, RJ Springall… - Oncogene, 2007 - nature.com
Basal-like breast cancers form a distinct subtype of breast cancer characterized by the
expression of markers expressed in normal basal/myoepithelial cells. Breast cancers arising …
expression of markers expressed in normal basal/myoepithelial cells. Breast cancers arising …
[HTML][HTML] Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival
LG Fulford, JS Reis-Filho, K Ryder, C Jones… - Breast Cancer …, 2007 - Springer
Abstract Introduction Cytokeratin (CK) 14, one of several markers expressed in normal
myoepithelial/basal cells, is also expressed in a proportion of breast carcinomas. Previous …
myoepithelial/basal cells, is also expressed in a proportion of breast carcinomas. Previous …
PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor–positive breast cancer
S Loi, B Haibe-Kains, S Majjaj… - Proceedings of the …, 2010 - National Acad Sciences
PIK3CA mutations are reported to be present in approximately 25% of breast cancer (BC),
particularly the estrogen receptor–positive (ER+) and HER2-overexpressing (HER2+) …
particularly the estrogen receptor–positive (ER+) and HER2-overexpressing (HER2+) …
Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast
LG Fulford, DF Easton, JS Reis‐Filho… - …, 2006 - Wiley Online Library
Aims: Cytokeratin (CK) 14, a myoepithelial marker, is also expressed in a proportion of
breast carcinomas. There is evidence that these tumours show a differing metastatic pattern …
breast carcinomas. There is evidence that these tumours show a differing metastatic pattern …
A role for Id-1 in the aggressive phenotype and steroid hormone response of human breast cancer cells
CQ Lin, J Singh, K Murata, Y Itahana, S Parrinello… - Cancer research, 2000 - AACR
The helix-loop-helix protein Id-1 inhibits the activity of basic helix-loop-helix transcription
factors, and is an important regulator of cell growth and tissue-specific differentiation. We …
factors, and is an important regulator of cell growth and tissue-specific differentiation. We …
High level expression of p27kip1 and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27kip1 and degree of …
S Fredersdorf, J Burns, AM Milne… - Proceedings of the …, 1997 - National Acad Sciences
The expression of cyclin-dependent kinase inhibitor p27kip1 in human tumors and normal
tissues was investigated using a panel of novel anti-p27kip1 mAbs. An inverse correlation …
tissues was investigated using a panel of novel anti-p27kip1 mAbs. An inverse correlation …
[HTML][HTML] Comparison of basal-like triple-negative breast cancer defined by morphology, immunohistochemistry and transcriptional profiles
P Gazinska, A Grigoriadis, JP Brown, RR Millis, A Mera… - Modern Pathology, 2013 - Elsevier
Basal-like invasive breast cancer is an important clinical group because of its association
with a triple-negative phenotype defined by the lack of expression of estrogen, progesterone …
with a triple-negative phenotype defined by the lack of expression of estrogen, progesterone …
RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers
S Irshad, F Flores-Borja, K Lawler, J Monypenny… - Cancer research, 2017 - AACR
Cancer cells tend to metastasize first to tumor-draining lymph nodes, but the mechanisms
mediating cancer cell invasion into the lymphatic vasculature remain little understood. Here …
mediating cancer cell invasion into the lymphatic vasculature remain little understood. Here …