We analyzed 156 primary neuroblastoma tumor samples for loss of heterozygosity at the
distal short arm of chromosome 1 (1p LOH). We also compared 1p LOH with known clinical …

The tumor necrosis factor receptor 2 (TNFR2) gene localizes to 1p36. 2, a genomic region
characteristically deleted in neuroblastomas and other malignancies. In addition, TNFR2 is …

Cellular, cytogenetic, and molecular evidence indicates that chromosome band 1p36 is
often deleted in neuroblastoma cell lines and tumours, suggesting the presence of one or …

Human Krüppel-related 3 (HKR3) is a zinc finger gene that maps within chromosome
subbands 1p36. 2-. 3, a region postulated to contain a tumour suppressor gene associated …

TheKrüppel-type zinc finger proteins are members of a conserved family of transcription
factors that are important in developmental regulation. Altered expression of several of these …

Mutations of CDKN2 have been found recently in melanoma and many other tumor types.
Neuroblastoma shares with melanoma a neuroectodermal origin and a high incidence of …

Molecular analysis of cells from cytology specimens can help to establish a diagnosis in
ambiguous cases. However, mutations in heterogeneous samples might not be detected …

Molecular analysis of clinical samples has been hampered by the lack of fresh or frozen
specimens and the presence of contaminating background cells within samples obscuring …