Angiogenesis, the development of new blood vessels from the existing vasculature, is an
essential component of solid tumour growth and metastasis. Several angiogenic factors are …

Tumors of the pituitary gland are usually benign adenomas and account for 10% of all
intracranial neoplasms. Five pituitary tumors have previously been reported to harbor …

Although uterine leiomyomas constitute the commonest benign tumour in women, the
regulation of their growth is poorly understood. It is believed that angiogenesis, the process …

Non-neoplastic epithelial lesions of the vulva (NNEDV) lichen sclerosus (LS) and squamous
hyperplasia (SH) have been implicated in the pathogenesis of squamous cell carcinoma of …

Tumor formation may result from the activation of dominant oncogenes or by inactivation of
recessive, tumor suppressor genes. The role of such mutations in the development of …

OBJECTIVE: A pilot study was performed to investigate the relationship between vulvar
vestibulitis syndrome and estrogen receptor expression. STUDY DESIGN: Women with a …

BACKGROUND: Although uterine fibroids are very common, their pathogenesis and clinical
behaviour are poorly understood. Since they may be prevalent in some families, we …

The p53 protein, a negative regulator of cell growth, plays an important role in the
pathogenesis of many human tumours following gene mutation and/or deletion. We …

Squamous cell carcinoma of the vulva (SCC) accounts for about 4% of all gynaecological
malignancies. It has an incidence of about 1.8 per 100,000. However, after the age of 75 the …

Lichen sclerosus (LS) has a known association with the development of squamous cell
carcinoma of the vulva. The purpose of this study was to investigate molecular markers …