Expression of p53 in leukoplakia and squamous cell carcinoma of the oral mucosa: correlation with expression of Ki67

S Kannan, GJ Chandran, KR Pillai… - Clinical molecular …, 1996 - ncbi.nlm.nih.gov
Aim—To study p53 expression in relation to proliferative status in normal and nondysplastic,
dysplastic and malignant lesions of the oral mucosa. Method—The standard avidin-biotin …

Ultrastructural variations and assessment of malignant transformation risk in oral leukoplakia

S Kannan, P Balaram, MR Pillai, GJ Chandran… - … -Research and Practice, 1993 - Elsevier
Oral cancer is the most common malignancy in India, having a well defined precancerous
state, leukoplakia. Various follow-up studies have shown that only 4 to 18% of oral …

Ultrastructure of oral squamous cell carcinoma: a comparative analysis of different histological types

S Kannan, CC Kartha, GJ Chandran, MR Pillai… - European Journal of …, 1994 - Elsevier
Twenty-five oral carcinomas and five normal oral epithelial specimens were studied using
light and electron microscopy. All histological types (well differentiated squamous cell …

Ultrastructural analysis of the adjacent epithelium of oral squamous cell carcinoma

S Kannan, P Balaram, GJ Chandran, MR Pillai… - British Journal of Oral …, 1996 - Elsevier
Fifteen biopsies of the immediate adjacent epithelium of oral squamous cell carcinoma were
examined under light and electron microscopy. Light microscopic examination of one micron …

Differential expression of cytokeratin proteins during tumour progression in oral mucosa.

S Kannan, P Balaram, GJ Chandran, MR Pillai… - Epithelial Cell …, 1994 - europepmc.org
The expression pattern of cytokeratin filaments in epithelia has been shown to be dependent
on their type and grade of differentiation. The type of expression of cytokeratin in a cell may …

Expression of lectin-specific cellular glycoconjugates during oral carcinogenesis

S Kannan, P Balaram, GJ Chandran, MR Pillai… - Journal of cancer …, 1993 - Springer
The binding pattern of two lectins, concanavalin A (ConA) and peanut agglutin (PNA), in
various phases of tumour progression in the oral epithelium was studied. These included …

Potential biological markers for the staging of tumor progression in oral mucosa: a multivariate analysis

S Kannan, GJ Chandran, P Balaram… - … journal of biological …, 1996 - journals.sagepub.com
A recent trend in cancer control programmes is the development of early detection strategies
and chemoprevention of premalignant lesions. The present study evaluates the potential of …

The immunohistochemistry of solid tumours: potential problems for new laboratories.

R Pillai, S Kannan, GJ Chandran - The National Medical Journal of …, 1993 - europepmc.org
Immunohistochemistry has become an important tool for tumour typing and has the potential
to improve the histopathological diagnosis of neoplasms. However, the large number of …

Expression of galactoside-specific endogenous lectins and their ligands in human oral squamous cell carcinoma

S Kannan, HJ Gabius, GJ Chandran, MR Pillai… - Cancer letters, 1994 - Elsevier
Human endogenous lectins have a wide spectrum of biological functions. The present study
analyses the expression of β-galactoside specific and N-acetyl-d-galactosamino specific …

[CITATION][C] Immunohistochemical analysis of ras p21 expression in normal, pre‐malignant and malignant oral mucosa

S Kannan, P Balaram, MR Pillai… - … journal of cancer, 1993 - Wiley Online Library
1989). A n analysis of 44 oral leukoplakia samples by immunohistochemical staining for ras
p21 showed none of them to be any different from their normal countelparts (Azuma et al …