Cyclooxygenase-2 expression in human esophageal carcinoma

KC Zimmermann, M Sarbia, AA Weber, F Borchard… - Cancer research, 1999 - AACR
On the basis of epidemiological observations that nonsteroidal anti-inflammatory drugs
reduce the risk of esophageal carcinoma, we studied the expression of cyclooxygenase-2 …

Prevalence and Heterogeneity of KRAS, BRAF, and PIK3CA Mutations in Primary Colorectal Adenocarcinomas and Their Corresponding Metastases

SE Baldus, KL Schaefer, R Engers, D Hartleb… - Clinical Cancer …, 2010 - AACR
Purpose: Epidermal growth factor receptor (EGFR) antibody therapy is established in
patients with wild-type KRAS colorectal carcinoma; however, up to 50% of these patients do …

Survivin-ΔEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties

C Mahotka, M Wenzel, E Springer, HE Gabbert… - Cancer research, 1999 - AACR
Recently, a novel antiapoptosis gene, ie, survivin, was identified as a structurally unique
member of the inhibitor of apoptosis protein family. Survivin expression is turned off during …

Mechanisms of tumor metastasis: cell biological aspects and clinical implications

R Engers, HE Gabbert - Journal of cancer research and clinical oncology, 2000 - Springer
The clinical course–and hence the prognosis–of patients suffering from malignant tumors
are essentially determined by the capability of tumor cells to metastasize. During the past …

German S3-guideline" Diagnosis and treatment of esophagogastric cancer"

M Moehler, SE Al-Batran, T Andus, M Anthuber… - Zeitschrift fur …, 2011 - elibrary.ru
MOEHLER M.* 1, AL-BATRAN SE, ANDUS T., ANTHUBER M., ARENDS J., ARNOLD D.,
AUST D., BAIER P., BARETTON G., BERNHARDT J., BOEING H., BÖHLE E., BOKEMEYER …

HER2 expression in gastric cancer: rare, heterogeneous and of no prognostic value–conclusions from 924 cases of two independent series

H Grabsch, S Sivakumar, S Gray… - Analytical Cellular …, 2010 - content.iospress.com
Background: Patients with gastric cancer (GC) have a poor survival and biologicals such as
Trastuzumab have not been used routinely in these patients. Existing data on HER2 …

Prognostic significance of CD8+ T cell and macrophage peritumoral infiltration in colorectal cancer

Y Funada, T Noguchi, R Kikuchi… - Oncology …, 2003 - spandidos-publications.com
The purpose of this study was to evaluate the prognostic significance of CD8+ T cell and
macrophage peritumoral infiltration in patients with colorectal cancer. A total of 97 …

Prospective randomized trial comparing magnetic resonance imaging (MRI)-guided in-bore biopsy to MRI-ultrasound fusion and transrectal ultrasound-guided …

C Arsov, R Rabenalt, D Blondin, M Quentin, A Hiester… - European urology, 2015 - Elsevier
Background A significant proportion of prostate cancers (PCas) are missed by conventional
transrectal ultrasound-guided biopsy (TRUS-GB). It remains unclear whether the combined …

Molecular characterization of commonly used cell lines for bone tumor research: a trans‐European EuroBoNet effort

L Ottaviano, KL Schaefer, M Gajewski… - Genes …, 2010 - Wiley Online Library
Usage of cancer cell lines has repeatedly generated conflicting results provoked by
differences among subclones or contamination with mycoplasm or other immortal …

Prognostic value of E‐cadherin expression in 413 gastric carcinomas

HE Gabbert, W Mueller, A Schneiders… - … journal of cancer, 1996 - Wiley Online Library
Abstract E‐cadherin is Ca2+‐dependent intercellular adhesion molecule known to exert an
invasion‐suppressor function. In the present study, E‐cadherin expression was …