Inadequate surgical margins represent a high risk for adverse clinical outcome in breast-
conserving therapy (BCT) for early-stage breast cancer. The majority of studies report …

Background Bile duct injury (BDI) is a dreaded complication of cholecystectomy, often
caused by misinterpretation of biliary anatomy. To prevent BDI, techniques have been …

The prognosis in advanced-stage ovarian cancer remains poor. Tumor-specific
intraoperative fluorescence imaging may improve staging and debulking efforts in …

Purpose: To provide proof of principle of safety, breast tumor–specific uptake, and positive
tumor margin assessment of the systemically administered near-infrared fluorescent tracer …

Growth factors may play an important role in tumour growth and angiogenesis by their
influence on tumour cell proliferation or their effect on neovascularization. The aim of the …

Background Optimum cytoreductive surgery combined with hyperthermic intraperitoneal
chemotherapy (HIPEC) is essential for the curative treatment of peritoneal carcinomatosis of …

Forty-two patients with clinical stage IIIA or IIIB breast cancer were treated with neoadjuvant
chemotherapy followed by mastectomy and radiotherapy. The median follow-up was 32 …

Aims: Hypoxia‐inducible factor‐1 (HIF‐1) is the key transcription factor regulating the
cellular response to hypoxia, including angiogenesis. Growth factors play an important role …

Cyclin D1 overexpression, detected by standard immunohistochemistry, was correlated with
other prognostic variables and its prognostic value was evaluated in a group of 148 invasive …

In 42 patients with locally advanced breast cancer treated with neoadjuvant chemotherapy
followed by surgery and radiation therapy, the effects of chemotherapy on tumor …