Introduction: Ongoing studies on the inhibition of gene expression at the mRNA level have
identified several types of specific inhibitors such as antisense oligonucleotides, small …

The concentration of microcystins (MCs) produced during blooms depends on variations in
both the proportion of strains containing the genes involved in MC production and the MC …

Homopyrimidine oligodeoxynucleotides recognize the major groove of the DNA double helix
at homopurine. homopyrimidine sequences by forming local triple helices. Phenanthroline …

An acridine derivative was covalently linked to the 5'end of a homopyrimidine
oligonucleotide. Specific binding to a homopurine-homopyrimidine sequence of duplex DNA …

DNA is prone to structural polymorphism: its three-dimensional structure can differ markedly
from the classical double helix. Nucleic acid structures composed of more than two strands …

Seminal studies using post-mortem brains of patients with Alzheimer's disease evidenced
aberrant insulin-like growth factor 1 receptor (IGF1R) signalling. Addressing causality, work …

Microcystins (MCs) are hepatotoxins with potent inhibitor activity of protein phosphatases
PP1 and PP2A. These non-ribosomal peptides are getting more and more attention due to …

Homopyrimidine oligodeoxynucleotides recognize the major groove of the DNA double helix
at homopurine. homopyrimidine sequences by forming local triple helices. The …

Since the late 1980s, much research has been devoted to the strategies that families use in
France to avoid sending their children to the public schools assigned to them by the carte …

Chronic and subchronic toxicity resulting from exposure to microcystins (MCs) receives
increasing attention due to the risk of bioaccumulation of these toxins by aquatic animals …