The following paper summarises a number of international research projects being
undertaken to understand the mechanical properties of natural cellulose fibres and …

Continuous synthesis of all cellular components requires their constant turnover in order for
a cell to achieve homeostasis. To this end, eukaryotic cells are endowed with two …

Oxidative stress reflects a disturbance in the balance between the production and
accumulation of reactive oxygen species (ROS). ROS are scavenged by the antioxidant …

Background High plasma HDL cholesterol is associated with reduced risk of myocardial
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes …

We performed a meta-analysis of 14 genome-wide association studies of coronary artery
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of …

Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …

Prostate cancer is the second most common cancer in men worldwide and causes over
250,000 deaths each year. Overtreatment of indolent disease also results in significant …

Mass cytometry enables high-dimensional, single-cell analysis of cell type and state. In
mass cytometry, rare earth metals are used as reporters on antibodies. Analysis of metal …

Autophagy is the cellular homeostatic pathway that delivers large cytosolic materials for
degradation in the lysosome. Recent evidence indicates that autophagy mediates selective …

We propose a method for rejection sampling from any univariate log‐concave probability
density function. The method is adaptive: As sampling proceeds, the rejection envelope and …