Article Text

Download PDFPDF

Demystified ... the polymerase chain reaction.
  1. K R Baumforth,
  2. P N Nelson,
  3. J E Digby,
  4. J D O'Neil,
  5. P G Murray
  1. Biomedical Research Laboratories, School of Health Sciences, University of Wolverhampton, UK.


    Since its initial description over twenty years ago the PCR has become one of the most valuable and flexible tools available to biomedical research. Subsequently, refinements and modifications to the basic approach, many of which have been described in this review, have enabled the application of the PCR to many areas of diagnostic medicine and have ensured its rapid acceptance as a routine test in many pathology disciplines. The growing importance of molecular approaches to the diagnosis of disease, particularly in histopathology, will continue to secure an ever expanding role for the PCR in diagnostic pathology.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.