Article Text

Download PDFPDF

The aetiology of idiopathic Parkinson's disease
  1. D B Ramsden1,
  2. R B Parsons1,
  3. S L Ho2,
  4. R H Waring3
  1. 1Department of Medicine, Division of Medical Science, University of Birmingham, Queen Elizabeth Hospital, Birmingham B15 2TH, UK
  2. 2Division of Neurology, Department of Medicine, University of Hong Kong, Hong Kong, China
  3. 3School of Biochemistry, University of Birmingham
  1. Dr Ramsden D.B.Ramsden{at}


Agents potentially involved in the aetiology of idiopathic Parkinson's disease are discussed. These include factors regulating dopaminergic neurogenesis (Nurr 1, Ptx-3, and Lmx1b) and related proteins, together with genes involved in familial Parkinson's disease (α synuclein, parkin, and ubiquitin carboxy terminal hydroxylase L1), and endogenous and environmental agents.

  • Parkinson's disease
  • environmental agents
  • transcription factors
  • α synuclein
  • parkin
  • ubiquitin carboxy terminal hydroxylase L1
View Full Text

Statistics from


    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.