PT  - JOURNAL ARTICLE
AU  - D R Brigstock
AU  - R Goldschmeding
AU  - K-i Katsube
AU  - S C-T Lam
AU  - L F Lau
AU  - K Lyons
AU  - C Naus
AU  - B Perbal
AU  - B Riser
AU  - M Takigawa
AU  - H Yeger
TI  - Proposal for a unified CCN nomenclature
AID  - 10.1136/mp.56.2.127
DP  - 2003 Apr 01
TA  - Molecular Pathology
PG  - 127--128
VI  - 56
IP  - 2
4099  - http://mp.bmj.com/content/56/2/127.short
4100  - http://mp.bmj.com/content/56/2/127.full
SO  - Mol Pathol2003 Apr 01; 56
AB  - A proposal is put forth to unify the nomenclature of the CCN family of secreted, cysteine rich regulatory proteins. In the order of their description in the literature, CCN1 (CYR61), CCN2 (CTGF), CCN3 (NOV), CCN4 (WISP-1), CCN5 (WISP-2), and CCN6 (WISP-3) constitute a family of matricellular proteins that regulate cell adhesion, migration, proliferation, survival, and differentiation, at least in part through integrin mediated mechanisms. This proposal is endorsed by the International CCN Society and will serve to eliminate confusion from the multiple names that have been given to these molecules.