Table 1

The range of glycosyl phosphatidylinositol (GPI) linked proteins

A partial list of proteins that are linked to the cell membrane by a GPI anchor and are therefore missing in paroxysmal nocturnal haemoglobinuria cells.
Enzymes
    Neutrophil alkaline phosphatase
    Acetylcholinesterase
    Lymphocyte 5`-ectonucleotidase
Adhesion molecules
    Neuronal cell adhesion molecule (CAM)
    LFA 3 (CD58)
    Blast-1
    CD66
    CD67
Complement regulatory proteins
    Decay accelerating factor (DAF/CD55)
    Membrane inhibitor of reactive lysis (MIRL/CD59)
    C8 binding protein
Receptors
    Fc gamma receptor (FcγRIII/CD16)
    CD14
    Urokinase-type plasminogen activator receptor (u-PAR/CD87)
Blood group antigens
    Cromer (CD55)
    Yt
    JMH
    Dombrock
Others
    CAMPATH-1 (CD52)
    CD24
    Carcinoembryonic antigen (CEA)
    Scrapie prion protein