Lesion | Pathology | Exon | Mutation | bp | Codon | Result |
---|---|---|---|---|---|---|
Pathology: DCIS, ductal carcinoma in situ; IDC, infiltrating ductal carcinoma; Intermediate, morphological features of LCIS and DCIS; LCIS, lobular carcinoma in situ. | ||||||
del., deletion. | ||||||
1 | DCIS | 6 | 9 bp del., insert T | 786–794 | 262–265 | Early stop |
2 | DCIS | |||||
3 | LCIS | |||||
4 | Intermediate | |||||
5 | DCIS | 6 | 9 bp del., insert T | 786–794 | 262–265 | Early stop |
6 | LCIS | |||||
7 | Intermediate | 6 | 9 bp del., insert T | 786–794 | 262–265 | Early stop |
8 | LCIS | |||||
9 | Intermediate | |||||
10 | Intermediate | 6 | 9 bp del., insert T | 786–794 | 262–265 | Early stop |
11 | DCIS | |||||
12 | DCIS | 6 | CCC → CTC | 779 | 260 | Pro → Leu |
6 | 9 bp del., insert T | 786–794 | 262–265 | Early stop | ||
13 | IDC | 6 | 9 bp del., insert T | 786–794 | 262–265 | Early stop |