Table 2

Correlation between initial area of involvement and spread and generalisation of dystonia and progression to parkinsonism in patients with X linked dystonia parkinsonism (XDP; n = 373) as of year 2000

		Present status
Initial area of involvement	Duration of illness (years)	Focal n (%)	Segmental n (%)	Multifocal n (%)	Generalised n (%)	Parkinsonian n (%)
One hundred and five patients died; the status of dystonia at time of death was considered.
Lower extremities	<2	4 (80)	2 (17)	2 (28)	37 (53)	0
n = 122 (33%)	2–5	1 (20)	5 (42)	2 (28)	25 (35)	1 (4)
	5–10	0	3 (25)	0	9 (12)	4 (15)
	10–15	0	1 (8)	3 (44)	0	2 (7)
	>15	0	1 (8)	0	0	20 (74)
	Total	5	12	7	71	27
Upper extremities	<2	0	1 (25)	0	13 (42)	0
n = 52 (14%)	2–5	0	1 (25)	2 (40)	14 (45)	0
	5–10	0	1 (25)	1 (20)	3 (10)	1 (8)
	10–15	0	1 (25)	2 (40)	1 (3)	2 (17)
	> 15	0	0	0	0	9 (75)
	Total	0	4	5	31	12
Cervix and shoulder	<2	0	3 (25)	0	29 (47)	0
n = 92 (25%)	2–5	2 (67)	4 (33)	2 (50)	27 (43)	2 (18)
	5–10	0	4 (33)	0	5 (8)	2 (18)
	10–15	1 (33)	0	2 (50)	1 (2)	4 (36)
	>15	0	1 (9)	0	0	3 (28)
	Total	3	12	4	62	11
Trunk	<2	0	1 (50)	0	1 (33)	0
n = 5 (1%)	2–5	0	1 (50)	0	1 (33)	0
	5–10	0	0	0	1 (33)	0
	10–15	0	0	0	0	0
	>15	0	0	0	0	0
	Total	0	2	0	3	0
Craniofacial	<2	0	1 (6)	1 (20)	24 (38)	0
n = 102 (27%)	2–5	1 (50)	4 (25)	2 (40)	33 (52)	2 (12)
	5–10	0	5 (31)	1 (20)	5 (8)	1 (6)
	10–15	1 (50)	3 (19)	0	1 (2)	6 (38)
	>15	0	3 (19)	1 (20)	0	7 (44)
	Total	2	16	5	63	16