Influence of histopathological markers, individually and in combination (NPI), on overall survival and disease free survival
| Variable | OS | DFS | N |
|---|---|---|---|
| Survival is in months (median (SEM)). | |||
| LAC, locally advanced carcinoma; NPI, Nottingham prognostic index. | |||
| Tumour size | |||
| ⩽2 cm | >228 | >228 | 33 |
| >2⩽5 cm | 96 (35) | 41 (36) | 49 |
| >5 cm | 23 (6) | 12 (2) | 26 |
| p Value | <0.0001 | <0.0001 | |
| Histological grade | |||
| I/II | >228 | >228 | 52 |
| III | 57 (11) | 29 (7) | 56 |
| p Value | <0.001 | <0.001 | |
| Lymph node stage | |||
| 0 | >212 | >212 | 33 |
| 1–3 | 100 (20) | 71 (42) | 26 |
| 4 | 91 (13) | 31 (19) | 23 |
| LAC | 30 (9) | 17 (4) | 26 |
| p Value | <0.0001 | <0.0001 | |
| NPI | |||
| Good | >228 | >228 | 9 |
| Moderate | >228 | >228 | 45 |
| Poor | 91 (39) | 23 (7) | 28 |
| LAC | 30 (9) | 17 (4) | 26 |
| p Value | <0.05 | <0.0001 | |