Table 4

Influence of immunohistochemical markers, individually and in combination (IHPI), on overall survival and disease free survival

VariableOSDFSN
Survival is in months (median (SEM)).
ER, oestrogen receptor; IHPI, immunohistochemical prognostic index; LAC, locally advanced carcinoma; PR, progesterone receptor.
c-erbB-2
    Negative142 (17)94 (17)41
    Positive58 (8)31 (5)67
    p Value<0.05NS
p53
    Negative100 (28)71 (35)75
    Positive57 (6)34 (7)33
    p Value<0.05NS
ER
    Positive>212>21236
    Negative57 (9)31 (5)72
    p Value<0.001<0.01
PR
    Positive>212>21240
    Negative55 (4)29 (5)68
    p Value<0.0001<0.0001
IHPI
    Good>212>21232
    Moderate96 (35)34 (10)23
    Poor51 (8)29 (6)53
    p Value<0.0001<0.001