Clinicopathological parameters in relation to p34cdc2 expression in tumour nuclei (p34cdc2TN)
| p34cdc2TN expression | p Value | ||||
|---|---|---|---|---|---|
| 1+ | 2+ | 3+ | 4+ | ||
| ER, oestrogen receptor; p34cdc2bn, p34cdc2 expression in benign breast tissue; p34cdc2TC, p34cdc2 expression in tumour cytoplasm; PR, progesterone receptor. | |||||
| Age (years) | |||||
| <50 | 6 | 17 | 12 | 5 | |
| ⩾50 | 8 | 22 | 22 | 2 | 0.702 |
| Menopausal | |||||
| Pre | 4 | 16 | 11 | 4 | |
| Post | 9 | 22 | 23 | 3 | 0.663 |
| T size | |||||
| T1 | 8 | 16 | 19 | 1 | |
| T2 | 6 | 23 | 15 | 6 | 0.47 |
| Grade | |||||
| 1 | 5 | 12 | 4 | – | |
| 2 | 6 | 19 | 13 | – | |
| 3 | 3 | 8 | 17 | 7 | <0.001 |
| p34cdc2TC | |||||
| <10% | 8 | 17 | 4 | – | |
| ⩾10% | 5 | 21 | 29 | 7 | <0.001 |
| p34cdc2bn | |||||
| <10% | 11 | 26 | 21 | 4 | |
| ⩾10% | 1 | 3 | 7 | 1 | 0.154 |
| p53 | |||||
| <10% | 13 | 30 | 23 | 3 | |
| ⩾10% | 1 | 6 | 10 | 4 | 0.005 |
| p21WAF1 | |||||
| <6% | 8 | 20 | 14 | 6 | |
| ⩾6% | 6 | 19 | 20 | 1 | 0.875 |
| ER | |||||
| Negative | 6 | 13 | 13 | 5 | |
| Positive | 8 | 24 | 20 | 2 | 0.364 |
| PR | |||||
| Negative | 6 | 18 | 17 | 5 | |
| Positive | 8 | 21 | 16 | 2 | 0.244 |
| Relapse | |||||
| No | 13 | 32 | 31 | 6 | |
| Yes | 1 | 7 | 3 | 1 | 0.900 |
| Death | |||||
| No | 13 | 36 | 31 | 6 | |
| Yes | 1 | 3 | 3 | 1 | 0.624 |