Table 6

Univariate analysis of examined parameters for disease free survival (DFS)

Total (n)Relapse (n)Median DFS (CI)p Value
Multivariate analysis for DFS: p34cdc2bn, p = 0.001; p34cdc2TC, p = 0.074.
CI, confidence interval; ER, oestrogen receptor; p34cdc2bn, p34cdc2 expression in benign breast tissue; p34cdc2TC, p34cdc2 expression in tumour cytoplasm; p34cdc2TN, p34cdc2 expression in tumour nuclei; PR, progesterone receptor.
Age (years)
    <5040373 (64–82)0.1042
    ⩾50549
Menopausal
    Pre35273 (63–83)0.1341
    Post57968 (58–78)
T size
    T144467 (65–69)0.5192
    T250875 (57–93
Grade
    121267 (56–78)0.9964
    238675 (54–96)0.7221
    335469 (64–74)0.4791
p34cdc2TN
    <10%14158 (49–67)0.1321
    ⩾10%801172 (64–80)
p34cdc2TC
    <10%29563 (56–70)0.0158
    ⩾10%62773 (55–91)
p34cdc2 bn
    <10%62868 (61–75)0.0030
    ⩾10%121102 (26–178)
p53
    <10%691168 (61–75)0.5671
    ⩾10%21069 (63–75)
p21WAF1
    <6%48868 (64–72)0.5019
    ⩾6%46472 (53–91)
ER
    Negative37468 (61–75)0.7945
    Positive54770 (60–80)
PR
    Negative46667 (61–73)0.4512
    Positive47673 (61–85)