Table 2

Composition and characteristics of the large clusters

Cluster identityNo of members (men)Age rangeNo. of diagnosing hospitalsNo. of health authority districtsKnown ethnic groupsCountry of birthAntimicrobial resistanceSputum smear positivePulmonary diseaseImmunosuppressive conditionsKnown risk factorsTransmission category
BA=black African; BC=black Caribbean; ISC=Indian subcontinent; C=Chinese; W=white; Rif=rifampicin; INH=isonazid; PZA=pyrazinamide; STR=streptomycin; ETH=ethambutol.
Transmission categories: A=confirmed link; B=possible link; C=no link identified.
Confirmed links: 1171 (husband and wife and four adjacent postcodes); 4143 (family and social contacts).
390812 (7)15–761178 BA, 1 ISC8 Somalia, 1 India1 MDR, 4 STR331 renal disease, 1 diabetes, 1 Down’s syndrome1 refugee, 1 homeless hostelB
206610 (7)33–90874W, 1 BC, 1 BA, 1 C1 UK, 1 China, 1 Nigeria, 1 IrelandAll sensitive681 lung cancer, 1 diabetes, 1 sarcoidosis (treated with steroids)3 alcoholic (inc 1 prison, 1 homeless), 2 difficult to treatB
9057 (7)29–64534W, 1 BC4 UKAll sensitive351 diabetes, 1 HIV +ve3 alcoholic (inc 1 HIV +ve), 1 homeless, 2 substance abuse, 1 non-compliantB
43507 (5)22–62532W, 1 BA, 1 BC, 1 ISC4 UK, 1 Pakistan, 1 NigeriaAll sensitive352 diabetesC
11716 (3)25–72412 W, 2 BC4 UK1 Rif, INH, PZA, STR; 1 Rif, INH, PZA, ETH241 non-Hodgkin’s lymphoma1 HIV +veA
41436 (5)33–66446 W2 UK, 1 IrelandAll sensitive263 alcoholic, 1 HIV +veA