Specific types of K-ras mutations identified and their frequencies
| Mutation type (all codon 12) | Adenomas (n=18)* | Carcinomas (n=22) |
|---|---|---|
| The three “other” mutations in the carcinomas were: codon 12, GGT→GCT; codon 13, GGC→GAC; codon 9, a 6 bp insert. | ||
| *Two adenomas each had two different Ki-ras mutations. | ||
| GGT→GAT | 9 | 9 |
| GGT→GTT | 9 | 5 |
| GGT→TGT | 1 | 3 |
| GGT→AGT | 1 | 0 |
| GGT→CGT | 0 | 2 |
| Other | 0 | 3 |