Clinical and laboratory observationCongenital idiopathic growth hormone deficiency associated with prenatal and early postnatal growth failure†
References (18)
- et al.
Somatotrophin in antenatal and perinatal growth and development
Lancet
(1969) Concepts relating the pituitary growth hormone to somatic growth of the normal child
Am J Dis Child
(1960)- et al.
The infancy-childhood-puberty model of growth: clinical aspects
Acta Paediatr Scand Suppl
(1989) - et al.
Infancy growth pattern related to growth hormone deficiency
Acta Paediatr Scand
(1988) - et al.
The ontogeny of somatotrophic binding sites in ovine hepatic membranes
Endocrinology
(1983) The role of pituitary hormones, growth factors and insulin in the regulation of fetal growth
- et al.
Isolated human growth hormone deficiency due to the hGH-I gene deletion with (type I-A) and without (the Israeli type) hGH antibody formation during hGH therapy
Acta Endocrinol (Copenh)
(1990) - et al.
Isolated growth hormone (GH) deficiency type I-A associated with a double deletion in the human GH gene cluster
J Clin Endocrinol Metab
(1986) - et al.
Birth data for patients who later develop growth hormone deficiency: preliminary analysis of a national register
Acta Paediatr Scand Suppl
(1990)
Cited by (165)
The necessity of magnetic resonance imaging in the evaluation of pediatric growth hormone deficiency: Lessons from a large academic center
2021, Growth Hormone and IGF ResearchCitation Excerpt :The lack of consistency in priming practices within our institution regarding children undergoing provocative GH testing may be a study weakness. However, this practice is not uniformly done by pediatric endocrinologists and it is a conditional recommendation based on recent guidelines [19,22–24]. Another weakness could be the small number of children with tumors all of which were craniopharyngiomas.
Successful use of an artificial placenta–based life support system to treat extremely preterm ovine fetuses compromised by intrauterine inflammation
2020, American Journal of Obstetrics and GynecologyCitation Excerpt :Similarly, direct fetal infusion of IGF-1 promotes fetal substrate uptake and inhibits fetal catabolism.86 In contrast to the postnatal situation, the dominant driver of circulating fetal IGF-1 regulator is not only the growth hormone (GH)87–89 but also fetal insulin, which in turn is predominantly regulated by fetal glucose availability.90,91 Thus, in this study, inappropriate nutrition (inappropriate glucose or insulin level), excessive corticosteroid dose (especially Dex) that might interfere with GH pulsation and decrease total GH secretion and IGF-1,92,93 and the absence of AF-derived IGF-1 may combine to result in an overall deficiency of IGF-1 levels and become a factor in growth restriction.
Abnormal Fetal Growth
2020, Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical ManagementAbnormal Fetal Growth
2019, Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical ManagementTranscriptome analyses reveal molecular mechanisms that regulate endochondral ossification in amphibian Bufo gargarizans during metamorphosis
2018, Biochimica et Biophysica Acta - General SubjectsCitation Excerpt :GH has been reported to stimulate growth of cartilage and other tissues by increasing cell number rather than cell size [57]. Previous studies have found that GH deficiency resulted in impaired growth in children and decreased bone mineral density in adults [51, 112, 120]. In our study, the expression level of GH peaked at G42 in B. gargarizans during metamorphosis.
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