Abstract
The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of Epstein-Barr virus has been established using the dideoxynucleotide/M13 sequencing procedure. Many RNA polymerase II promoters have been mapped and the mRNAs from these promoters have been assigned to the latent or early/late productive virus cycles. Likely protein-coding regions have been identified and three of these have been shown to encode a ribonucleotide reductase, a DNA polymerase and two surface glycoproteins.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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DNA Restriction Enzymes
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DNA, Viral*
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Gene Expression Regulation*
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Genes, Viral*
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Herpesvirus 4, Human / genetics*
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RNA Polymerase II / genetics
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RNA Polymerase III / genetics
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RNA, Messenger / genetics
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RNA, Viral / genetics
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Transcription, Genetic
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Viral Proteins / genetics
Substances
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DNA, Viral
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RNA, Messenger
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RNA, Viral
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Viral Proteins
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RNA Polymerase II
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RNA Polymerase III
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DNA Restriction Enzymes
Associated data
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GENBANK/V01509
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GENBANK/V01554
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GENBANK/V01555