Abstract
The pathogenesis of oral squamous cell carcinoma involves recognised carcinogens in tobacco and/or alcohol but other factors, including viruses, may also have a role. This paper reviews the gene changes revealed in oral carcinoma, the evidence implicating viruses, and mechanisms whereby viruses may affect gene function.
MeSH terms
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Carcinoma, Squamous Cell / genetics*
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Carcinoma, Squamous Cell / microbiology*
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Gene Expression Regulation, Neoplastic / genetics
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Gene Expression Regulation, Neoplastic / physiology
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Genes, Tumor Suppressor / genetics*
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Humans
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Mouth Neoplasms / genetics*
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Mouth Neoplasms / microbiology*
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Oncogenes / genetics*
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Oncogenic Viruses / genetics
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Oncogenic Viruses / physiology*