We herein present an overview of the upcoming 5th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …

Very low levels of circulating monoclonal B‐cell subpopulations can now be detected in
apparently healthy individuals using flow cytometry. We propose the term 'monoclonal B‐cell …

A relatively high number of different subsets of B‐cells are generated through the
differentiation of early B‐cell precursors into mature B‐lymphocytes in the bone marrow (BM) …

The European Myeloma Network (EMN) organized two flow cytometry workshops. The first
aimed to identify specific indications for flow cytometry in patients with monoclonal …

Background A diagnosis of chronic lymphocytic leukemia (CLL) requires a count of over
5000 circulating CLL-phenotype cells per cubic millimeter. Asymptomatic persons with fewer …

Importance Numerous studies have evaluated the prognostic value of minimal residual
disease (MRD) in patients with multiple myeloma (MM). Most studies were small and varied …

The eradication of minimal residual disease (MRD) in chronic lymphocytic leukaemia (CLL)
predicts for improved outcome. However, the wide variety of MRD techniques makes it …

Minimal Residual Disease Assessed by Multiparameter Flow Cytometry in Multiple Myeloma:
Impact on Outcome in the Medical Researc Page 1 Minimal Residual Disease Assessed by …

Molecular and cellular markers associated with malignant disease are frequently identified
in healthy individuals. The relationship between these markers and clinical disease is not …

This report represents a further update of the consensus panel criteria for the assessment of
clinical response in patients with W aldenström macroglobulinaemia (WM). These criteria …