Towards the introduction of the 'Immunoscore'in the classification of malignant tumours

…, HK Angell, A Berger, C Lagorce… - The Journal of …, 2014 - Wiley Online Library
Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine …

[HTML][HTML] Cancer classification using the Immunoscore: a worldwide task force

…, E Wang, J O'Donnell-Tormey, C Lagorce… - Journal of translational …, 2012 - Springer
Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation
of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor …

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

…, N Haicheur, A Kirilovsky, A Berger, C Lagorce… - The Lancet, 2018 - thelancet.com
Background The estimation of risk of recurrence for patients with colon carcinoma must be
improved. A robust immune score quantification is needed to introduce immune parameters …

[PDF][PDF] In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer

…, M Tosolini, G Bindea, C Lagorce… - Journal of clinical …, 2009 - academia.edu
In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal
Cancer Page 1 In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With …

[HTML][HTML] Impact of EGFR expression on colorectal cancer patient prognosis and survival

JP Spano, C Lagorce, D Atlan, G Milano, J Domont… - Annals of oncology, 2005 - Elsevier
Background Epidermal growth factor receptor (EGFR) is overexpressed in many types of
cancers, especially colorectal cancer (CRC), and seems to reflect more aggressive …

[HTML][HTML] Multicenter international society for immunotherapy of cancer study of the consensus immunoscore for the prediction of survival and response to …

…, A Kirilovsky, A Berger, C Lagorce… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
PURPOSE The purpose of this study was to evaluate the prognostic value of Immunoscore
in patients with stage III colon cancer (CC) and to analyze its association with the effect of …

Prognostic and predictive values of the immunoscore in patients with rectal cancer

…, N Haicheur, AM Todosi, A Kirilovsky, C Lagorce… - Clinical Cancer …, 2014 - AACR
Purpose: To determine whether the tumor immune infiltrate, as recently evaluated with the
Immunoscore methodology, could be a useful prognostic marker in patients with rectal …

A diagnostic biopsy-adapted immunoscore predicts response to neoadjuvant treatment and selects patients with rectal cancer eligible for a watch-and-wait strategy

…, B Mlecnik, N Haicheur, T Fredriksen, C Lagorce… - Clinical Cancer …, 2020 - AACR
Purpose: No biomarker to personalize treatment in locally advanced rectal cancer (LARC) is
currently available. We assessed in LARC whether a diagnostic biopsy-adapted …

Cyclooxygenase‐2 is expressed frequently and early in Barrett's oesophagus and associated adenocarcinoma

C Lagorce, F Paraf, D Vidaud, A Couvelard… - …, 2003 - Wiley Online Library
Aims: To establish the prevalence of cyclooxygenase‐2 (COX‐2) expression in a large
series of resected Barrett's adenocarcinoma and associated preneoplastic lesions and to …

[HTML][HTML] Signet-ring cell carcinoma of the stomach: Impact on prognosis and specific therapeutic challenge

…, T Voron, G Perkins, C Lagorce-Pages… - World Journal of …, 2015 - ncbi.nlm.nih.gov
While the incidence of gastric cancer has decreased worldwide in recent decades, the
incidence of signet-ring cell carcinoma (SRCC) is rising. SRCC has a specific epidemiology …