PURPOSE To provide evidence-based recommendations to practicing clinicians on
management of patients with stage III non–small-cell lung cancer (NSCLC). METHODS An …

The balance between protein acetylation and deacetylation controls several physiological
and pathological cellular processes, and the enzymes involved in the maintenance of this …

Purpose• Some in the oncology community contend that patients undergoing chemotherapy
and/or radiation therapy should not use food supplement antioxidants and other nutrients …

Background New technologies for the detection of early-stage ovarian cancer are urgently
needed. Pathological changes within an organ might be reflected in proteomic patterns in …

Pathologic states within the prostate may be reflected by changes in serum proteomic
patterns. To test this hypothesis, we analyzed serum proteomic mass spectra with a …

The modeling of forces during needle insertion into soft tissue is important for accurate
surgical simulation, preoperative planning, and intelligent robotic assistance for …

During skeletal myogenesis, genomic reprogramming toward terminal differentiation is
achieved by recruiting chromatin-modifying enzymes to muscle-specific loci,. The relative …

Importance To our knowledge, there have been no clinical trials of ultra-high-dose-rate
radiotherapy delivered at more than 40 Gy/sec, known as FLASH therapy, nor first-in-human …

Background Escalating healthcare costs are necessitating the practice of value-based
oncology. It is crucial to critically evaluate the economic impact of influential but expensive …

Fusion of undifferentiated myoblasts into multinucleated myotubes is a prerequisite for
developmental myogenesis and postnatal muscle growth. We report that deacetylase …